Bub1b mitochondria

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August undefined, 2024

WebOct 13, 2024 · High expression of BUB1B can increase proliferation, migration, and invasion of prostate cancer cells . MiR-200c-5p inhibits the proliferation, migration, and invasion of HCC cells by down-regulating MAD2L1 [ 33 ], which suggested that the expression of MAD2L1 is significantly higher in HCC and related to the poor prognosis of HCC. WebBUB1B. The antibodies are designated mAB for monoclonal and pAb for polyclonal. The release of the Human Protein Atlas in which the antibody was first published. All assays through which the antibody has been validated. Assays&annotation provide a detailed description of the different assays.

BubR1 antibody (11504-2-AP) Proteintech - ptglab

WebJan 1, 2024 · BUB1B plays a role in mitochondrial function. Mitochondria are involved in energy synthesis, apoptosis and other important biological processes and are vital for cell survival and function. Recently, mitochondrial dysfunction has been reported to participate in tumorigenesis (Davis et al., 2024; Vyas, Zaganjor & Haigis, 2016; Zhang et al., 2024 ... WebFeb 23, 2024 · BUB1B plays a role in mitochondrial function. Mitochondria are involved in energy synthesis, apoptosis and other … goodiford mill fishery \u0026 leisure

Early embryonic death of BUBR1- null embryos. (A) E3.5 …

WebBUB1B: Mitotic checkpoint serine/threonine-protein kinase BUB1 beta; Essential component of the mitotic checkpoint. Required for normal mitosis progression. The mitotic … WebBUB1B. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a … WebBUB1B encodes a mitotic spindle check point (serine/threonine kinase B). ... ARE increases both ROS production and mitochondrial damage and suppresses the in vitro tumor … goodiford fishing

(PDF) Combined expression of BUB1B, DLGAP5, and PINK1 as …

WebPROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. BUB1B INFORMATION. Proteini. Full gene name according to HGNC. BUB1 mitotic checkpoint … WebNotably, Bub1b+/- female mice presented late-onset subfertility, and they were more sensitive to oxidative stress than wild-type female controls, mimicking the clinical … goodiford mill fishery and leisure parkWebJan 29, 2024 · The findings revealed that AFB1-associated liver fibrosis and HCC combined genes were linked to cell process disruptions, the BUB1B and RRM2 genes were identified as hub genes, and the BUB1B gene was significantly increased in JAK-STAT signaling gene sets pathways as well as having an immunotherapy-related impact. good igns for games

"WebTo explore the specific function of BUB1B in HCC in vivo and in vitro, we performed the flow cytometry, Cell Counting Kit-8, 5-ethynyl-2'-deoxyuridine incorporation, colony formation, Transwell, wound-healing, subcutaneous tumor growth, and metastasis assays. Additionally, we identified the BUB1B-regulated pathways involved in HCC by using gene ... " - Bub1b mitochondria

Bub1b mitochondria

Subcellular - BUB1B - The Human Protein Atlas

WebOct 7, 2024 · BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B) is a conserved multifunctional protein that is vital for the function of mitotic spindle checkpoint and … WebBUB1B. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. Assigned HPA protein class (es) for the encoded ...

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WebNov 2, 2011 · BUB1B, DLGAP5, and PINK1 expression was assessed by quantitative PCR in 53 ACTs from 52 patients - 24 pediatric and 28 adults (one pediatric patient presented a bilateral asynchronous ACT). WebDownload scientific diagram BUB1B plays a role in mitochondrial function. Total ATP production was detected in different treatment groups (A). Mitochondrial membrane …

WebFeb 8, 2024 · DNA. Functions. Disease. Aging. Mitochondria are often referred to as the powerhouses of the cell. They help turn the energy we take from food into energy that the cell can use. But, there is more ... WebMar 21, 2024 · This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has …

WebJun 20, 2004 · Bub1b H/H mice had a normal appearance until 2–3 months of age (Fig. 1f; compare with wild-type mouse in Fig. 1e) but typically developed cachexia and lordokyphosis at 3–6 months of age (Fig ... WebBUB1B (Mitotic checkpoint serine/threonine-protein kinase BUB1 beta), also named as BUBR1, MAD3Land SSK1, belongs to the BUB1 subfamily. Human BUB1B is a 120 kDa …

WebJan 11, 2024 · The reduction of BUB1B level or inhibition of BUB1B kinase activity in human cancer cells resulted in massive chromosome loss and apoptotic cell death 23. …

WebBUB1B is part of cluster 43 Non-specific - Cell proliferation with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated clustering, and therefore reflects how strongly associated it is to the cluster. goodiford mill fishery goodiford mill fishery cullomptonWebMar 21, 2024 · BUB1B (BUB1 Mitotic Checkpoint Serine/Threonine Kinase B) is a Protein Coding gene. Diseases associated with BUB1B include Premature Chromatid … goodiford mill campingWebApr 3, 2007 · MVA1 is caused by biallelic mutations in the BUB1B gene Description A severe developmental disorder characterized by mosaic aneuploidies, … good i hope in spanishWebBUB1B (a.k.a. BUB1beta, BUBR1, Bub1A, MAD3L, MVA1, SSK1, hBUBR1) Cloning Information Cloning method Gateway Cloning 5′ sequencing primer M13pUC-fwd 3′ sequencing primer M13rev (Common Sequencing Primers) Resource Information good ikea credit cardsWebBUB1B. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. good ign for valorantWebThe BUB1B gene provides instructions for making a protein called BUBR1, which is important for proper chromosome separation during cell division. Before cells divide, they … good ill do chords