Dynein axonemal heavy chain 8

Author: evwf

August undefined, 2024

WebRefSeq Summary (NM_001145154): Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. Two major classes of dyneins, axonemal and cytoplasmic, have been identified. DNAH14 is an axonemal dynein heavy chain (DHC) (Vaughan et al., 1996 [PubMed 8812413]).[supplied by … WebPR:000029434 dynein axonemal heavy chain 8 (term hierarchy) InterPro Domains. IPR003593 AAA+ ATPase domain. IPR026983 Dynein heavy chain. IPR041589 …

Ordered deployment of distinct ciliary beating machines in …

WebMay 1, 2001 · The dynein heavy chain is enormous, being approximately 4600 amino acid residues in length, more than twice the size of myosin II and more than four times the … WebDynein axonemal heavy chain 1 Curated. Alternative names. Axonemal beta dynein heavy chain 1; Ciliary dynein heavy chain 1; Heat shock regulated protein 1 (HSRF-1) … propane south berwick me

Role of Dynein Axonemal Heavy Chain 6 Gene Expression as a

WebMar 29, 2024 · DNAH8 dynein axonemal heavy chain 8 Gene ID: 1769, updated on 29-Mar-2024 Gene type: protein coding Also known as: hdhc9; ATPase; SPGF46. See all … WebMay 1, 2001 · The most highly divergent portion of the heavy chain sequence is the N-terminal ∼1300 residues. This portion of the protein forms the relatively short tail of dynein, and its sequence is best correlated with the functional class of the dynein isoform 6, 7, 8.Interactions within the N-terminal domain are important for heavy chain dimerization 8, … WebApr 13, 2024 · Outer dynein arms in the ciliary axoneme generate force for ciliary beating. Here, cryo-electron tomography study of the outer dynein arm from the unicellular alga C. reinhardtii revealed structures of multiple intermediate and prepower stroke states in the presence of ATP, as well as structural differences between in situ and in vitro … propane southern states

Dynein - Wikipedia

Web1 day ago · Outer dynein arms in the ciliary axoneme generate force for ciliary beating. Here, cryo-electron tomography study of the outer dynein arm from the unicellular alga … WebFeb 4, 2024 · DNAH8 is dynein axonemal heavy chain 8 protein expressed in SP and spermatids, which is involved in cell motility and sperm motility. It has been reported that DNAH8 variants lead to morphological abnormalities in the sperm flagella and male infertility . The fact that these changes in gene expression are found in RS of both transgenic … lactated ringers amazonWebDynein Axonemal Heavy Chain 8 promotes androgen receptor activity and associates with prostate cancer progression. Oncotarget May 28, 2016 propane space heater freeman gas

"WebMay 1, 2024 · In individual 2, one rare variant (c.9110A > G;p.(H3037R)) in the dynein axonemal heavy chain 11 gene (DNAH11), coding for another component of the outer dynein arm, was identified. We identified the likely genetic cause of SI and PCD in one individual, and a possibly significant heterozygosity in the other, both involving dynein … " - Dynein axonemal heavy chain 8

Dynein axonemal heavy chain 8

WebJun 7, 2024 · Fanconi anemia (FA), an X-linked genetic or autosomal recessive disease, exhibits complicated pathogenesis. Previously, we detected the mutated Dynein Axonemal Heavy Chain 2 (DNAH2) gene in 2 FA cases.Herein, we further investigated the potential association between DNAH2 and the homologous recombination repair pathway of FA. WebFeb 4, 2015 · Dynein axonemal heavy chain 11 Curated. Alternative names. Axonemal beta dynein heavy chain 11; Ciliary dynein heavy chain 11; Gene names. Name. DNAH11 Imported. Organism names. ... Dynein heavy chains probably consist of an N-terminal stem (which binds cargo and interacts with other dynein components), and the …

Did you know?

WebCoordinated movement of the dynein arms causes the entire axoneme to bend back and forth. IDAs and ODAs have different combinations of protein components (subunits) that … WebNumerous distinct dynein heavy chain genes have been isolated from Paramecium,7 Chlamydomonas,8,9 sea urchin,10 rat,11,12mouse,13 and human.13–16However, comparing the dynein heavy chain gene ...

WebDNAH8, dynein axonemal heavy chain 8 Vertebrate Orthologs 2 Human Diseases more Diseases 1 with Dnah8 mouse models; 1 with human DNAH8 associations Mutations, Alleles, and Phenotypes less Phenotype Summary 12 phenotypes from 1 allele in 1 genetic background 6 phenotype references Phenotype Overview WebJul 25, 2002 · Moreover, the axonemal dynein arms are composed of 1–3 heavy chains (400–500 kDa), a variable number of intermediate chains (45–140 kDa), and one or more light chains (8–28 kDa) . To date, exclusion studies of the DNAH9 ( 14 ), DNAI2 (13, ††), and LC8 (††) genes have been reported.

WebDynein heavy chain (HC) motors are members of the ATPases associated with cellular activities (AAA)+ class of ATPases that includes enzymes with a diverse array of functions in organisms ranging from bacteria to mammals. From: Methods in Enzymology, 2013 Related terms: Flagellum Cilium Kinesin Axoneme Dynactin View all Topics Add to Mendeley Web1 day ago · The beating of motile cilia requires the coordinated action of diverse machineries that include not only the axonemal dynein arms, but also the central apparatus, the radial spokes, and the microtubule inner proteins. ... 2009) and by immunostaining of ODA/IDA heavy chains in vertebrates (Dougherty et al., 2016; Fliegauf et al., 2005; Oltean et ...

WebAxonemal dyneins generate force through hydrolysis of ATP and binding to microtubules. [provided by RefSeq, Jan 2012] Other designations. dynein axonemal heavy chain 8, … propane southport ncWebJul 10, 2024 · we design to provide clues to prove relationship between dynein heavy chain gene 5 (DNAH5) gene alterations and asthenozoospermia. This also provides a reference for patients to choose a reasonable treatment plan or genetic counseling to assist reproductive reproduction. Patients concern: In the present study, we screened 143 … lactated ringers and chronic kidney diseaseWebFeb 5, 2008 · Dynein axonemal heavy chain 6 Curated Alternative names Axonemal beta dynein heavy chain 6 Ciliary dynein heavy chain 6 Gene names Name DNAH6 Imported Synonyms DNAHC6, DNHL1, HL2, KIAA1697 Organism names Organism Homo sapiens (Human) Taxonomic identifier 9606 NCBI Taxonomic lineage propane southington ctEach molecule of the dynein motor is a complex protein assembly composed of many smaller polypeptide subunits. Cytoplasmic and axonemal dynein contain some of the same components, but they also contain some unique subunits. Cytoplasmic dynein, which has a molecular mass of about 1.5 megadaltons (MDa), is a dimer of dimers, containing approximately twelve polypeptide sub… propane space heater fhaWebJul 3, 2024 · Among the well-characterized axonemal protein complexes, the outer dynein arms (ODAs), through ATPase activity of their heavy chains (HCs), play a major role for cilia and flagella beating. However, the contribution of the different HCs (γ-type: DNAH5 and DNAH8 and β-type: DNAH9, DNAH11, and DNAH17) in ODAs from both organelles is … lactated ringers and cirrhosisWebMar 21, 2024 · Gene ID: 25981, updated on 5-Aug-2024 Summary This gene encodes an inner dynein arm heavy chain that provides structural support between the radial spokes and the outer doublet of the sperm tail. propane spa heater reviewsWebDNAH.bc.12 A gene on chromosome 3p14.3 that encodes a dynein heavy chain protein, which hydrolyses ATP to ADP, mediating the movement of respiratory cilia and producing force towards the minus ends of microtubules. propane space heater indoor walmart