Ku80 molecular weight
WebWhen using primary antibodies produced in mouse to detect proteins with a molecular weight in the range of 50 kDa, we recommend using Rabbit Anti-Mouse IgG (Light Chain … Ku80 is a protein that, in humans, is encoded by the XRCC5 gene. Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V(D)J recombination, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian immune system. In addition to its role in NHEJ, Ku is required for telomere length maintenance and subtelomeric …
Ku80 molecular weight
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Web28 feb. 2024 · Ku70 Antibody (E-5) is a mouse monoclonal IgG 1 κ Ku70 antibody, cited in 80 publications, provided at 200 µg/ml. raised against amino acids 302-609 mapping at … Ku is a dimeric protein complex that binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. Ku is evolutionarily conserved from bacteria to humans. The ancestral bacterial Ku is a homodimer (two copies of the same protein bound to each other). Eukaryotic Ku is a heterodimer of two polypeptides, Ku70 (XRCC6) and Ku80 (XRCC5), so named because the molecular weight of the human Ku proteins is around 70 kDa a…
Web27 feb. 2014 · Comparison of the cDNAs with the genomic sequences revealed that the KU70 mRNA spans over 3,047 bp containing 16 exons separated by 15 introns, whereas the KU80 mRNA spans over 3,426 bp containing 11 exons separated by 10 introns (Figure 1 ). Web28 aug. 2024 · The number average molecular weight (M n) is given by 2.2.7 , where M i is molecular weight of a molecule of oligomer n, and N i is number of molecules of that molecular weight. Total weight = Σ ∞ i = 1MiNi. Total number = Σ ∞ i = 1Ni. Mn = Σ ∞ i = 1MiNi Σ ∞ i = 1Ni. Example 2.2.8.
WebComparison of the cDNAs with the genomic sequences revealed that the KU70 mRNA spans over 3,047 bp containing 16 exons separated by 15 introns, whereas the KU80 mRNA spans over 3,426 bp containing 11 exons separated by 10 introns (Figure 1). WebXRCC5/Ku80 Polyclonal Antibody for IF, IHC, IP, WB, ELISA Host / Isotype Rabbit / IgG Reactivity human, mouse and More (1) Applications WB, IP, IHC, IF, CoIP, ChIP, ELISA …
Web25 mei 2007 · Mol. Weight (Da) 70642.0 Isoelectric Point 6.29 Median Abundance (molecules/cell) 1273 +/- 329 Alleles Curated mutant alleles for the specified gene, …
WebThe Ku70/80 complex was first identified in 1981 by Mimori et al. as a high-molecular-weight nuclear protein and as an antigen recognized by auto-antibodies in sera from patients with ... This dimer is mediated by a domain swap mechanism of the conserved C-terminal helix of Ku80. In this dimer, DNA ends present in each DNA-PK run ... megan fox rose boyWeb3 jan. 2010 · Human Ku80 mRNA is stable in Xenopus oocytes post-microinjection Eighteen hours after the in vitro-transcribed mRNAs were injected into Xenopus oocytes that were metabolically labeled with 35 S-methionine, full length Ku70 polypeptide from the oocyte cytoplasm and nucleus could be radioimmunoprecipitated with the anti-T7 Tag antibody … na na before you get a whoopinWeb1 mrt. 2001 · ATP-dependent DNA helicase 2 subunit KU80 EC number EC:3.6.4.12 ( UniProtKB ENZYME Rhea) Alternative names ATP-dependent DNA helicase 2 subunit … megan fox rousseWeb19 jun. 2001 · Total Structure Weight: 150.97 kDa Atom Count: 9,472 Modelled Residue Count: 1,072 Deposited Residue Count: 1,229 Unique protein chains: 2 Unique nucleic acid chains: 2 Display Files Download Files 1JEY Crystal Structure of the Ku heterodimer bound to DNA PDB DOI: 10.2210/pdb1JEY/pdb NDB: PD0220 Classification: DNA BINDING … nanabel\u0027s country kitchen las vegas nvWebKu is a heterodimeric protein composed of two subunits (Ku70 and Ku80) originally identified by researchers as autoantigens associated with several autoimmune diseases including scleroderma, polymyositis, and systemic lupus erythematosus (1). megan fox rogue reviewWeb27 feb. 2014 · To further improve targeting frequency, the KU70 and KU80 homologs in R. toruloides were isolated and characterized in detail. A KU70-deficient mutant (∆ku70e) … nana bed goes to the gateWeb5 okt. 2024 · The Ku70–Ku80 (Ku) heterodimer binds rapidly and tightly to the ends of DNA double-strand breaks and recruits factors of the non-homologous end-joining (NHEJ) repair pathway through molecular ... nana bediako cheddar networth